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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
The top drug-food interactions forCialisare listed below by solid line:
  1. Caffeine may increase the blood pressure-lowering effects of tadalafil when taken with other medications that act as fluid compartments (Ex. riociguat).
  2. Cialis may enhance the blood pressure-lowering effects of alcohol with the use of tadalafil.
  3. Lifestyle factors may also play role in the enhancement of blood pressure-lowering effects of tadalafil.

For a complete list of the drug-food interactions, please refer to the manufacturer's

Tadarise Interaction Report

For more information about the drug-food interaction and the specific drug, please refer to the

  1. Caffeine may enhance the blood pressure-lowering effects of tadalafil when taken with other medications that act as fluid compartments (Ex.

Before you begin taking Tadalafil generic, its important to carefully read the Patient Information Leaflet. Make sure to review it each time you get a refill.

Take Tadalafil dosage orally, either with or without food, as directed by your healthcare provider. Tadalafil dosage should not exceed more than once a day. Swallow the tablet whole. Do not split it or crush unless advised.

Your daily dosage will depend on your medical condition, how you respond to medications, and any other medications you currently take. Before you take ED treatment pills, ensure that you inform your healthcare service provider of any prescription drugs, over-the-counter medicines, and any other supplements you take.

If you are also using finasteride alongside Tadalafil to treat any symptoms of benign prostatic hyperplasia (BPH), discuss the duration of treatment and dosage you will need with your healthcare provider.

For erectile dysfunction (ED), tadalafil citrate may be prescribed in two ways:

  • You may take it as needed, usually at least 30 minutes before sexual activity, with its effects potentially lasting up to 36 hours.
  • Your doctor may recommend taking generic Cialis regularly, once a day.

Follow your doctors instructions carefully based on your specific needs and condition.

If you are using tadalafil citrate medication for ED dysfunction and BPH, take it daily as directed by your doctor. To ensure you do not forget, take it at the same time each day.

Keep your healthcare practitioner informed if your medical condition does not improve or worsens during treatment.

Read the "Tadalafil generic" label carefully and follow any regulations on the date being taken and for the duration of treatment. If you need help taking tadalafil generic medication more than twice a day, consult your doctor for down-sized inserts, or ask your doctor for a generic prescription.Take Tadalafil generic before every meal you can imagine. Tadalafil generic medication is intended for adult men aged 18 or over.

For diagnosed erectile dysfunction, tadalafil citrate may be prescribed in two ways:

  • You may take it usually once or twice a day.

Follow your doctor's instructions carefully based on your specific needs and condition.

If you are using tadalafil citrate medication for ED dysfunction and BPH, take it regularly on a daily basis.

If you need help taking tadalafil generic at the same time, consult a doctor for down-sized inserts, or ask your doctor for a generic prescription.

Tadalafil generic is intended for adult men aged 18 or over.

For ED, tadalafil citrate may be prescribed in two ways:

  • Your doctor may recommend taking generic Cialis regularly.

If you are using tadalafil citrate medication for ED dysfunction and BPH, tadalafil generic may be prescribed in several different ways. Tadalafil generic may be taken alongside of doctor's advice;

    • You may take tadalafil generic medication for ED.
    • Your doctor may suggest taking generic Cialis regularly or once a day.
    • If you are also using generic Cialis for ED dysfunction and BPH, tell your doctor.

    If you miss a dose of tadalafil generic, take it as soon as you can, but not more than once a day. If you are not sure about the dose, take it as soon as you can, but not more than once a day.

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